Ayesha Ghayur, M.D., Ph.D.

Assistant Professor of Pathology

  • Office: Coal Building 818
  • Telephone: (606) 218-5425
  • E-mail: ayeshaghayur@upike.edu

Pathology I
Pathology II
Pathology & Disease Processes

MBBS, Aga Khan University, Karachi, Pakistan
PhD (Medical Sciences), McMaster University, Hamilton, Canada

Ghayur A, Elahi Q, Patel C, Raj R. Rhabdomyolysis-induced acute kidney injury in a patient with non-compliance to levothyroxine therapy. Endocrinol Diabetes Metab Case Rep. 2021 Jun 1;2021:21-0034.

Ghayur A, Padwal MK, Liu L, Zhang J, Margetts PJ. SMAD3-dependent and -independent pathways in glomerular injury associated with experimental glomerulonephritis. Am J Physiol Renal Physiol. 2019 Jul 1;317(1):F152-F162.

Siddique I, Curran SP, Ghayur A, Liu L, Shi W, Hoff CM, Gangji AS, Brimble KS, Margetts PJ. Gremlin promotes peritoneal membrane injury in an experimental mouse model and is associated with increased solute transport in peritoneal dialysis patients. Am J Pathol. 2014 Nov;184(11):2976-84.

Ghayur A, Margetts PJ. Transforming growth factor-beta and the glomerular filtration barrier. Kidney Res Clin Pract. 2013 Mar 1;32(1):3-10.

Ghayur A, Liu L, Kolb M, Chawla A, Lambe S, Kapoor A, Margetts PJ. Adenovirus-mediated gene transfer of TGF-β1 to the renal glomeruli leads to proteinuria. Am J Pathol. 2012 Mar;180(3):940-951.

Educational Commission for Foreign Medical Graduates (ECFMG): Certification,
Philadelphia, PA, USA, 2019

Research Fellow: Department of Biochemistry & Molecular Biology, Drexel University College of Medicine, Philadelphia, PA, USA
Research Fellow: Ludwig Institute for Cancer Research, University College London, London, England
Post-doctoral Fellowship: Division of Nephrology, St. Joseph’s Hospital, McMaster University, Hamilton, Canada

Role of TGF-beta in proteinuria
Fibrotic pathways in glomerulonephritis
Proteinuria and podocyte de-differentiation
Epithelial to mesenchymal transition in fibrosis