Guichun Han, Ph.D.

Associate Professor of Physiology

  • Office: Coal Building, Room 819
  • Telephone: (606) 218-5436
  • E-mail:

Human Physiology

Doctor of Philosophy, Biochemistry, Dalian Medical University, China

Master’s Degree, Physiology, Dalian Medical University, China

Bachelor of Medicine, Inner Mongolia Medical College, China

Yan H, Yang W, Zhou F, Li X, Pan Q, Shen Z, Han G, Newell-Fugate A, Tian Y, Majeti R, Liu W4, Xu Y, Wu C, Allred K, Allred C, Sun Y, Guo S. Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1. Diabetes. 2018 Nov 28. pii: db180638. doi: 10.2337/db18-0638 [Epub ahead of print].

Yu X, Zhang Q, Zhao Y, Schwarz BJ, Stallone JN, Heaps CL, Han G. The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries. PLoS One. 2018 Jan 23;13(1):e0191418. doi: 10.1371/journal.pone.0191418. eCollection 2018

Yu X, Zhang Q, Zhao Y, Schwarz BJ, Stallone JN, Heaps CL, Han G. Activation of G protein-coupled estrogen receptor 1 induces coronary artery relaxation via Epac/Rap1-mediated inhibition of RhoA/Rho kinase pathway in parallel with PKA. PLoS One. 2017 Mar 9;12(3):e0173085. doi: 10.1371/journal. pone.0173085. eCollection 2017.

Yang S, Jiang M, Grabowska MM, Li J, Connelly ZM, Zhang J, Hayward SW, Cates JM, Han G, Yu X. Androgen receptor differentially regulates the proliferation of prostatic epithelial cells in vitro and in vivo. Oncotarget. 2016 Oct 25;7(43):70404-70419. doi: 10.18632/oncotarget.11879.

Han G and White RE. GPER as a new therapeutic target for treating coronary artery disease. World Journal of Cardiology Jun 26: 6(6) 367-375, 2014

Internship was completed in one year in the hospital of Qiqihaer, Helongjiang province, China

Physiology; Pathophysiology; Cardiovascular Physiology; Pharmacology Cardiovascular physiology; vascular physiology and pharmacology, especially signaling pathways for estrogen and selective estrogen receptor modulator (SERM) effects on coronary circulation; molecular mechanisms of estrogen receptors in vascular remodeling and hypertension